Date of Graduation
Fall 12-17-2024
Document Type
Thesis
Degree Name
Master of Science (MS)
Department
Biology
Thesis Chair
Dr. Charles Watson
Abstract
Chitin is a major component of the exoskeleton of arthropods as well as the cell wall of fungi. This amino polysaccharide polymer provides structure and protection to these organisms and represents a significant barrier to digestion of arthropod prey and fighting fungal infections. Chitinases are enzymes that break down chitin. Smaller insectivores, based upon the higher surface-to-volume ratio of their even smaller prey, ingest a large amount of chitin per unit prey item. Therefore, they represent high-likelihood opportunities to bio prospect for novel chitinases that may be effective against pathogenic fungi. Fungal infections are notoriously difficult to treat, and they are the cause of ailments whose severity ranges from mild skin irritation to systemic infections that can lead to mortality. The purpose of this study is to document the activity of chitinase produced by a small vertebrate insectivore, Hemidactylus turcicus, and determine its utility as a source for future studies that will test the efficacy of these enzymes against potentially pathogenic fungi.
Recommended Citation
John, Alec, "The activity and origin of the chitinases in the gut of the Mediterranean House Gecko" (2024). Masters Theses. 29.
https://digitalcommons.tamusa.edu/masters_theses/29