Document Type
Article
Publication Date
2012
Abstract
Characterizing the phenotypic changes associated with aging in a short-lived primate is necessary in order to develop better translational models for human health, aging, and disease research. A population of conventionally housed marmoset monkeys was assessed to determine if phenotypes of body composition, hematology, and morphometrical measures were associated with age or risk of death. We found that the cause of mortality in older marmosets was more likely to be due to cardiac and chronic kidney disease than in younger marmosets. Older marmosets have decreased fat mass, morphometric measures, and serum albumin. Older marmosets are more likely to show a modified posture while at rest and this modified posture was significantly associated with an increased risk of imminent death. These assessments provide an initial definition of aged health in marmosets and a base for future translational aging research with this species.
Digital Object Identifier (DOI)
10.1155/2012/567143
Volume
2012
Repository Citation
Ross, Corinna N.; Davis, K.; Dobek, G.; and Tardif, S. D., "Aging Phenotypes of Common Marmosets (Callithrix Jacchus)" (2012). Biology Faculty Publications. 18.
https://digitalcommons.tamusa.edu/bio_faculty/18
Comments
© Hindawi. Published under Creative Commons Attribution License. Original published version available at https://doi.org/10.1155/2012/567143.
Ross, C., Davis, K., et al. (2012). Aging Phenotypes of Common Marmosets (Callithrix Jacchus). Journal of Aging Research, 2012, article # 567143.