Document Type

Article

Publication Date

10-2017

Keywords

Exercise Intervention, Flow-Mediated Dilation, Overweight and Obese Adults, Meta-Analysis

Abstract

The objective of this meta-analysis is to summarize the effect of exercise intervention on flow-mediated dilatation (FMD) in overweight and obese adults. We searched four electronic databases (PubMed/Medline, Scopus, and CINAHL) through June 2016 for relevant studies pertaining to the effectiveness of exercise intervention on FMD. Seventeen of the 91 studies identified met the inclusion criteria. Comprehensive Meta-Analysis software (version 3) was used to compute the standardized mean difference effect size (ES) and 95% CI using a random effects model. We calculated 34 ESs. We found that exercise intervention had medium and positive effects on FMD, with an overall ES of 0.522 (95% CI = 0.257, 0.786). Heterogeneity of ESs was observed (๐‘„๐‘ = 239, ๐‘ โ‰ค 0.001, ๐ผ 2 = 86.19), and the effect was moderated by comorbidity (๐‘„๐‘ = 6.39, df = 1, ๐‘ = 0.011). A large ES for the combination exercise, low intensity exercise, and comorbidity subgroups (ES = 0.82โˆผ1.24) was found. We conclude that while exercise intervention significantly improves FMD in overweight and obese adults, the effect may depend on the different characteristics of exercise intervention and on participantsโ€™ demographics.

Comments

Published in: International Journal of Vascular Medicine Volume 2017, Article ID 7532702, 11 pages https://doi.org/10.1155/2017/7532702

Publisher Citation

Son, Y., Kim, K., Jeon, S., Kang, M., Lee, S., & Park, Y. (2017). Effect of Exercise Intervention on Flow-Mediated Dilation in Overweight and Obese Adults: Meta-Analysis. International Journal of Vascular Medicine, 1โ€“11. https://doi.org/10.1155/2017/7532702

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